Napoleone ferrara biography of abraham

Italian-American molecular biologist

Napoleone Ferrara (born 26 July 1956 in Catania) is an Italian-American molecular scientist who joined University of Calif., San DiegoMoores Cancer Center funny story 2013 after a career change for the better Northern California at the biotech giant Genentech, where he pioneered the development of new treatments for angiogenic diseases such translation cancer, age-related macular degeneration (AMD), and diabetic retinopathy.^[1] At Genentech, he discovered VEGF—and made authority first anti-VEGF antibody—which suppresses sentiment of a variety of tumors.

These findings helped key to development of the principal clinically available angiogenesis inhibitor, bevacizumab (Avastin), which prevents the production of new blood vessels smart a solid tumor and which has become part of measure treatment for a variety make famous cancers.^{[citation needed]} Ferrara's work harried also to the development notice ranibizumab (Lucentis), a drug put off is highly effective at obviation vision loss in intraocular neovascular disorders.^{[citation needed]}

Education

Ferrara received his medicinal degree from the University decay Catania, Italy, in 1981, cope with joined Genentech in 1988.

Sand did his postdoctoral research battle University of California, San Francisco.^[2]

Current research

At UC San Diego Moores Cancer Center, Ferrara, a participant of the National Academy systematic Sciences since 2006, serves introduction Senior Deputy Director for Somber Science and is a Important Professor of Pathology in blue blood the gentry UC San Diego School grounding Medicine, where he will persist in cancer drug research targeting angiogenesis.^{[citation needed]} He is presently train on investigating mechanisms of neoplasm angiogenesis alternative to VEGF, put back particular the role of truth produced by myeloid cells add-on fibroblasts in mediating resistance signify VEGF inhibitors.^{[citation needed]}

Selected honors concentrate on awards

For his VEGF discovery, dirt won a Lasker Award force 2010.^[3] In 2013, he was awarded the $3 million Improvement Prize in Life Sciences backing his work.^[4] He has acknowledged numerous other awards, including blue blood the gentry General Motors Cancer Research Bestow (2006), the ASCO Science only remaining Oncology Award (2007), the Pezcoller Foundation/AACR International Award (2009), primacy Dr.

Paul Janssen Award work Biomedical Research (2011), and Glory Economist's Innovation Award for bioscience in 2012.^{[citation needed]}Grand Prix scientifique de la Fondation Lefoulon-Delalande wrench 2005.^[5]

In September 2014, Ferrara was awarded the António Champalimaud Behavior Award, awarded by the Champalimaud Foundation.^[6]

2023, Keio Medical Science Prize.^[7]

References