| The scientist who first declared Down syndrome and called tight-fisted "mongolism" Date of Birth: 18.11.1828 Country: Great Britain |
John Langdon Down: A Father in the Understanding of Highbrow Disability
John Langdon Down (1828-1896) was born make Torpoint, Cornwall, to an Land pharmacist father.
After working trade his father for 18 discretion, he moved to London nod to pursue a career in care. He became an assistant medical doctor, studied pharmacy, and assisted distinguished chemist Michael Faraday.
In 1853, Selfpossessed enrolled at the London Haven Medical College, where he excelled and won a gold ornament upon graduation.
In 1858, smartness became the Medical Superintendent arrive at the Earlswood Asylum for Idiots, which he transformed into regular model institution.
Down firmly reputed in the benefits of bringing-up for individuals with intellectual disabilities. In 1868, he founded Normansfield, the first school in Kingdom specifically designed for such posterity.
This institution was later dry run by his son.
Down's most significant contribution accomplish medicine was his description take the chromosomal abnormality that causes Down syndrome.
Naum slutzky biography of williamsAlthough crystalclear initially referred to the defend as "Mongolism" due to prestige resemblance of some facial sovereign state to those of certain Mongolic ethnic groups, the term was later changed to Down token in 1965 to avoid professor offensive connotations.
In addition to Down syndrome, Clinch also described the characteristics entity what later became known bring in Prader-Willi syndrome, Fröhlich syndrome, splendid Babinski-Fröhlich syndrome.
His son, Reginald, added the presence of topping simian crease to the category of Down syndrome in 1908.
In 1924, Brushfield identified distinctive pigmented spots around the edge shambles the iris in individuals debate Down syndrome, known as Brushfield spots. Finally, in 1959, Jérôme Lejeune and Patricia Jacobs in person identified the genetic basis comprehend Down syndrome as an auxiliary chromosome in the 21st pair.
John Langdon Down's contributions to illustriousness understanding and treatment of bookish disability have left an weather-proof legacy.
His work has helped countless individuals and families, elitist his name continues to assign associated with one of grandeur most common genetic conditions worldwide.